Methods: Screening of 12,364 participants

in a Danish health examination survey led to 1026 heavy drinkers of whom 772 were included and randomized to a BMI group (n = 391) or a control group (n = 381) receiving two leaflets about alcohol. Follow-up took place after 6 and 12 months including 670 and 616 participants respectively. The outcome measure was self-reported weekly alcohol consumption. Data were analysed according to the intention-to-treat principle. We used the Motivational Interviewing Treatment Integrity 3.0 code (MITI) as a quality control of the interventions delivered. Results: The intervention effect of the BMI was -1.0 drinks/week, Combretastatin A4 research buy but the effect was not significant. The MITI analysis showed that the quality of the BMI delivered was sub-optimal, as only one of four aspects was above the recommended level for beginning proficiency. Conclusion: We found no effect of a BMI in reducing alcohol consumption. The generalizability of the study is questionable, as individuals with the lowest level of education, low income and unmarried individuals are under-represented.”
“The aims of

this study were to determine the effects of body condition score (BCS), breed and dietary supplementation on the concentrations of leptin, insulin and glucose found in the blood obtained from hair sheep during the breeding season. A further aim was to investigate the possible association of fertility and prolificacy with these blood Navitoclax concentration metabolites, BCS and body weight (BW). All ewes were grazed in paddocks with ad libitum access to mineral salts and water. A total of 96 ewes were divided into two groups according selleck chemicals to breed and treatment: Santa Ines (supplemented or unsupplemented) (24 x 24)

and Morada Nova (supplemented or unsupplemented) (24 x 24). Blood samples, and BW and BCS information were collected during the breeding season. The statistical analyses were performed using the program PROC GLM from the SAS software. The leptin concentrations in hair sheep raised in a tropical climate were low. Little effect of breed, treatment or sample collection was found for blood insulin concentrations (p <0.05), although the values were higher in the supplemented groups from both breeds. Significant differences were observed in glucose concentrations between the breeds in the same sample collections, with the higher concentrations being found in the Santa Ines sheep (p < 0.05). The BCS for ewes that were not pregnant showed the highest correlation with leptin, insulin and glucose concentrations (r=0.53, 0.52 and 0.43, respectively). In the Morada Nova supplemented sheep (prolificacy: 1.45), there were verified correlations between BCS and BW, BCS and insulin concentration, and also between insulin and leptin concentrations. The present study shows that the Morada Nova breed has a higher reproductive efficiency than the Santa Ines breed.