This increased recruitment of STS areas in the blind for voice processing is in marked contrast with the usual cross-modal recruitment of occipital cortex. (c) 2009 Elsevier Ltd. All rights reserved.”
“Aversive stimuli capture attention and elicit increased neural activity, as indexed by behavioral, electrocortical and

hemodynamic measures; moreover, individual AZD9291 clinical trial differences in anxiety relate to a further increased sensitivity to threatening stimuli. Evidence has been mixed however as to whether aversive,, pictures elicit increased neural response when presented in unattended spatial locations. In the current study, ERP and behavioral data were recorded from 49 participants as aversive and neutral pictures were simultaneously presented in spatially attended and unattended locations; on each trial, participants made same/different judgments about pictures presented in attended locations. Aversive images presented in unattended locations resulted in increased error rate and reaction Ruboxistaurin cost time. The late positive potential (LPP) component of the ERP was only larger when aversive images were presented in attended locations, and this increase was positively correlated with self-reported state anxiety. Findings

are discussed in regard to the sensitivity of ERP and behavioral responses to aversive distracters, and in terms of increased neural processing of threatening stimuli in anxiety. (c) 2009 Elsevier Ltd. All rights reserved.”
“In the neuropsychological case series approach, tasks are administered that tap different cognitive domains, and differences within rather than across individuals are the basis for theorising; each individual is effectively their own control. This approach

is a mainstay of cognitive neuropsychology, and is particularly suited to the study of populations with heterogeneous deficits. However it has very rarely been applied to the study of cognitive PD0332991 ic50 differences in autism spectrum disorder (ASD). Here, we investigate whether this approach can yield information beyond that given by the typical group study method, when applied to an ASD population. Twenty-one high-functioning adult ASD participants and 22 IQ, age, and gender-matched control participants were administered a large battery of neuropsychological tests that would represent a typical neuropsychological assessment for neurological patients in the United Kingdom. The data were analysed using both group and single-case study methods. The group analysis revealed a limited number of deficits, principally on tests with a large executive function component, with no impairment in more routine abilities such as basic attending, language and perception. Single-case study analysis proved more fruitful revealing evidence of considerable variation in abilities both between and within ASD participants.