Conclusions: Appropriate care and monitoring of HDGF patients allows them to regain normal renal function and to achieve patient and renal survival rates similar to those of IGF and DGF patients. Copyright (C) 2012 S. Karger AG, Basel”
“Purpose: The aim of this study was to assess the adaptive response induced by low doses of ultraviolet-B (UVB, 290-320 nm) radiation in the Drosophila wing spot test.

Materials and methods: The adaptive response of Drosophila larvae to UVB light was studied by using a somatic mutation and recombination test (SMART).

The SMART system used was the wing spot test, which uses morphological markers of Autophagy inhibitor the wing blade. This in vivo test has shown to be very useful to study the induction of genetic damage in somatic cells, measuring loss of heterozygosity (LOH) resulting from BV-6 chemical structure gene mutation, mitotic recombination, chromosomal rearrangements or chromosome loss.

Results: To determine the induction of adaptive response, two-day-old Drosophila larvae were first irritated with an adaptive dose (58.3 J/m(2)), followed by different challenge doses (178, 224, 288, 338, and 386 J/m(2)). When the

results obtained in the different challenge doses were compared with those obtained following the application of adaptive plus challenge doses, significant decreases (74.7-80.8%) in a first experiment, and (65.6-78.4%) in a second experiment, were observed in the frequency of mutant spots on the wing blades.

Conclusions: Our results show that in Drosophila the adaptive response can be stimulated in vivo by UVB exposure.”
“The influence of the hydrostatic

pressure on the piezoelectric response for tetragonal BaTiO(3) and PbTiO(3) monodomain crystals is investigated using Landau-Ginzburg-Devonshire phenomenological approach. It is shown that hydrostatic pressure could enhance the piezoelectric properties in some directions of crystals. The piezoelectricy enhancement is attributed to the hydrostatic pressure-induced flattening of the elastic Gibbs free-energy profile and its corresponding dielectric softening. For BaTiO(3) Wnt inhibition at 285 K, with increasing pressure, the free-energy profile tends to become flat along the polar [001](c) direction, facilitating the dilatation and contraction of polarization. So the dielectric softens and the d(33) obviously increases in the [001](c) direction. But in the direction perpendicular to the polarization, the free-energy profile goes to steepen, which restrains the polarization rotation away from the [001](c) polar axis and in turn makes the shear piezoelectric coefficient d(15) decreased. As a result, the maximum longitudinal piezoelectric coefficient d*(33)(theta) initially going along [111](c) axis finally turns to be along [001](c) axis with pressure increasing.