(C) 2009 American Institute of Physics. [doi:10.1063/1.3253750]“
“Methods: HRQOL was assessed with
SF-36 and EuroQol (EQ-5D and EQ-VAS) and the patients were asked disease-specific questions.
Results: The 97 patients with AVNRT [53 +/- 16 years of age/65 women] and 79 patients with WPW [42 +/- 15 years of age/26 women] exhibited significantly lower HRQOL scores in SF-36 in the same seven of the eight scales: Physical functioning (PF), role-physical (RP), social functioning (SF), role-emotional (RE), general health (GH), vitality (VT), and mental health (MH) while there was no difference in bodily pain (BP) compared to their respective age- and gender matched Swedish reference group. HRQOL scores were
lower for patients MAPK inhibitor with AVNRT compared to WPW in the areas of PF (P < 0.001), BP (P < 0.05), and GH (P < 0.01) in SF-36, and the same was found in EQ-VAS (64.8 vs. 71.2, P < 0.05). Occurrence of episodes of tachycardia more often than once a month compared to less frequently than once a month was associated with significantly lower HRQOL in all eight scales in SF-36 (GH, RE, MH: P < 0.01 and PF, RP, BP, VT, SF: P < 0.001) and EQ-5D index (P < 0.001) and EQ-VAS (P < 0.05) Arrhythmia duration BV-6 research buy longer than one hour compared to patients with shorter duration of the tachycardia-affected GH in SF-36 negatively (P < 0.05). Patients who experienced symptoms not only during activity but also at rest scored lower
in SF-36 GH (P < 0.01) and SF (P < 0.05).
Conclusion: Measuring HRQOL in patients with WPW or AVNRT is an important way to evaluate and describe these patients’ life situation. These conditions were found to have a pronounced negative impact on HRQOL. The frequency of arrhythmia occurrence is one important factor to consider when setting priorities for treatment with RF-ablation.
(PACE Ulixertinib inhibitor 2009; 1299-1306).”
“Objective-To determine the electrophysiological changes in dogs with peripheral nerve sheath tumors (PNSTs), evaluate the prevalence of these changes, assess the correlation between spontaneous activity in epaxial muscles and proximal invasion by the tumor, and evaluate whether knowledge of electrophysiological changes could be helpful in the imaging diagnosis via CT or MRI.
Design-Retrospective case series.
Animals-51 dogs with a histologic (n = 18) or a suspected (33) diagnosis of PNST. Procedures Clinical, postmortem, and histologic reports and details of electrodiagnostic procedures and CT or MRI reports were studied. Twenty-four CT and 6 MRI reports for dogs with PNSTs were reviewed by a single observer blinded to the diagnosis.
Results-Only 2 of the 51 dogs had no electrophysiological changes.