The pooled eradication rate was 66.4% (99/149) by high throughput screening compounds ITT in experiment group and 67.4% (85/126) by ITT in control group. The incidences of total adverse effects were 21.7% (97/435) in the experimental groups and 26.4% (140/474) in the control groups. The pooled OR was 0.79 (95%CI: 0.34-1.85) by random effect model
(I 2 = 83.4%, P = 0.000). Conclusion: Available data suggest that the effectiveness of regimens with rifabutin, PPIs and amoxicillin for Helicobacter pylori rescue therapy may be not superior to that of control regimens. Key Word(s): 1. Helicobacter pylori; 2. amoxicillin; 3. rifabutin; 4. systemic review; 5. meta-analysis Presenting Author: KIKI MAHARANI Additional Authors: ARITANTRI DARMAYANI, PAULUS KUSNANTO, TRI YULI PRAMANA, M. selleck chemical TANTORO HARMONO Corresponding
Author: KIKI MAHARANI Affiliations: Moewardi Hospital, Moewardi Hospital, Moewardi Hospital, Moewardi Hospital Objective: It is generally known that Helicobacter pylori (H. pylori) infection is associated with renal dysfunction. Many reports suggest that chronic H. pylori infections may be associated with atherosclerosis and inflammations. Atherosclerosis and inflammation will decrease renal function. The aim of this study was to investigate the association between Helicobacter pylori infection and creatinin clearance in patient with dyspepsia. Methods: This retrospective study was conducted between Januari 2014 until Juni 2014 in Moewardi Hospital Surakarta. Inclusion criteria
was dyspepsia syndrome. Exclusion criteria was chronic kidney disease, chronic liver disease, malignancy, infection and diabetes mellitus. Glomerular filtration rate (eGFR) were estimated by Cockroft-Gault formula. H pylori infection identified by positive biopsi specimen from endoscopy. Statistical analysis using independence t-test and Pearson correlation test with SPSS 20, significant if p < 0,05. Results: There were 121 patient, 53 man and 68 woman with 34 positive H . pylori and 87 negative H pylori . The mean creatinin was 1,50 + 2,01 mg/dL, mean ureum 53,88 + 52,98 mg/dL, and mean eGFR 90,32 + 104,37 mL/min/1.73 m2 . There was negative correlation between h pilory infection 上海皓元医药股份有限公司 and eGFR in patient with syndrom dyspepsia (p:0,002, r:-0, 378). Key Word(s): 1. Helicobacter pylori; 2. dyspepsia syndrom; 3. estimated glomerolus filtration rate Presenting Author: HIROKI SHIMODA MEN Additional Authors: HIROKI SHIMODA, RIKA NAKANO Corresponding Author: HIROKI SHIMODA Affiliations: Jcho Takanawa Hospital, Jcho Takanawa Hospital Objective: Introduction : In Japan, due to the improved sanitation and hygiene, the prevalence of Helicobacter pylori infection has been decreasing among young people, but its prevalence is still high among middle-aged or elderly people. And more and more people are diagnosed with diabetes in today’s Japan.